Tiba’s biodegradable nanoparticle has a payload capacity which is an order of magnitude greater than traditional LNPs.  This allows our scientists to design more complex data structures that express a desired protein content at a well-defined ratio.  Tiba is developing novel algorithms and a database of annotated nucleic acid structures that allow us to rapidly develop candidate applications.  While our first focus is on prophylactic vaccines against infectious diseases, we are expanding the platform to:

• Auto-immune diseases and allergenic diseases
• Gene delivery and antibody expression
• Complex RNA circuits